Acetaminophen (Paracetamol) Journal of Pain and Symptom Management Figure 1: CMAJ TYLENOL [Acetaminophen] metabolism A lot of GLUTATHIONE is needed to deal with the Oxidative Stress generated by the CYP 450 metabolism of Tylenol. When people go to the ER for Tylenol Overdose Exposure to acetaminophen and all its metabolites upon 10, 15, and 20 mg kg intravenous acetaminophen in very preterm infants Pediatric Research Effect of Excipients on Acetaminophen Metabolism and Its Implications for Prevention of Liver Injury Ganetsky 2013 The Journal of Clinical Pharmacology Wiley Online Library Acetaminophen Use During Pregnancy and Neurodevelopmental Risk: Biological Plausibility1 Journal of Obstetrics and Gynaecology Canada