Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome Oral melanotic macule and primary oral malignant melanoma: Epidemiology, location involved, and clinical implications Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontics Why Is There a Dark Spot on My Lip? PDF] Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis. Semantic Scholar Changes in Oral Mucosa Associated with Melanotan II Injections: A Case Report