Evolution of Negative Cooperativity in Glutathione Transferase Enabled Preservation of Enzyme Function* Phase III Metabolism of Herbicides or Xenobiotics in Plants passel Daily Habits That Promote Detoxification Glutathione conjugation and protein modification resulting from metabolic activation of pesticide metalaxyl in vitro and in vivo ScienceDirect The Multifaceted Role of Glutathione S Transferases in Health and Disease There's a lot of misinformation about how the body detoxes. It's not just about sweat. It's a sophisticated two phase system driven by your liver, kidneys, and gut Phase I converts compounds