Cheilitis (lip inflammation): Causes and Treatment Can Dry Lips Be a Sign of Vitamin Deficiency? fatty15 Dry lips can often be a sign of certain vitamin deficiencies. The most common deficiencies associated with dry lips include: B Vitamins: Deficiencies in B vitamins, particularly B2 (riboflavin), B3 Zara Your lips can speak louder than you think Dry, cracked, pale, or dark each tells a story about your inner health. From vitamin deficiencies to hydration issues, your lips are 15 Signs and Symptoms of Vitamin C Deficiency How To Prevent Nutrient Deficiency Related Chapped Lips OnlyMyHealth