Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Pigmented Lesions of the Oral Mucosa Springer Nature Link This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips. Pigmented Lesions of the Oral Mucosa Pocket Dentistry Labial melanotic macule Labial melanotic macule