Our Science Nacuity Pharmaceuticals The Mechanism and Inflammatory Markers Involved in the Potential Use of N acetylcysteine in Chronic Pain Management 5 Antidote: NAC (N acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. Example: Hospitals use NAC as the standard treatment for APAP overdose. N ACETYLCYSTEINE (NAC) Full article: Perioperative N acetylcysteine: evidence and indications NAC [N AcetylCysteine] is a precursor of Glutathione. PICTURE: Glutathione is made from three amino acids and cysteine is one of them