Is it safe to drink while taking Tylenol? Heres why you should avoid Tylenol , First of all, it is full of colorful dyes, sugars, and additives., But the main reason is it depletes glutathione., Glutathione is one of the most Tylenol's Impact on Glutathione and Liver Damage Tylenol And Glutathione Invigor Medical Your livers unsung hero: Glutathione , Lets talk about what really happens when you take Tylenol (acetaminophen)., Your liver breaks down acetaminophen through several pathways. One pathway creates A Possible Antidote for Tylenol (Paracetamol) Overdose American Council on Science and Health